The efficacy of oral ribavirin in treatment of Crimean-Congo hemorrhagic fever in Iran
| Author | M Mardani | en |
| Author | M Keshtkar Jahromi | en |
| Author | K Holakoi Naini | en |
| Author | M Zinali | en |
| Issued Date | 2003-11-01 | en |
| Abstract | Background: Crimean-Congo Hemorrhagic fever is a fatal viral disease that occurs in some parts of Africa, Asia, Eastern Europe and Middle-East. Primarily it is a zoonosis but can be seen sporadically in humans. Recently outbreaks have been reported from Pakistan, Afghanistan, Saudi Arabia, United Arab Emirates and Iran. Objective: This study was performed to determine the effecacy of oral ribavirin in treament of CCHF cases by comparing the outcome in two treated and non-treated confirmed CCHF cases. Methods: In this retrospective study 81 confirmed CCHF cases (by serology or viral culture) were evaluated for the incidence of outcome (death or recovery) in the from of an analytic case-control study. Results were analyzed by statistical tests. Findings: From 69 proved CCHF cases who were treated by oral ribavirin and 12 cases who had received no drugs, 61 and 5 cases were survived respectively. Conclusion: Oral ribavirin with an efficacy of 91% can be an effective medical therapy for management of Crimean-Congo hemorrhagic fever. | en |
| DOI | https://doi.org/ | en |
| Keyword | Crimean-Congo Hemorrhagic Fever | en |
| Keyword | Oral Ribavirin | en |
| Keyword | Efficacy | en |
| Publisher | Brieflands | en |
| Title | The efficacy of oral ribavirin in treatment of Crimean-Congo hemorrhagic fever in Iran | en |
| Type | Research Article | en |
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