Prevalence of SARS-CoV-2 Specific Antibodies in the Staff of a Children's Hospital, in Tehran, Iran
| Author | Shahnaz Armin | en |
| Author | Fereshteh Karbasian | en |
| Author | Seyedeh Mahsan Hoseinialfatemi | en |
| Author | Roxana Mansour Ghanaie | en |
| Author | Sedigheh Rafiei Tabatabaei | en |
| Author | Seyed Alireza Fahimzad | en |
| Author | Maryam Rajabnejad | en |
| Author | Ghamartaj Khanbabaee | en |
| Author | Soheila Sadat Vaghefi | en |
| Author | Farid Imanzadeh | en |
| Author | Saeed Maham | en |
| Author | Raheleh Razmara | en |
| Author | Abdollah Karimi | en |
| Author | Peyman Eshghi | en |
| Author | Mahtab Maghsudlu | en |
| Author | Ali Arabkhazaeli | en |
| Orcid | Shahnaz Armin [0000-0002-4993-482X] | en |
| Orcid | Fereshteh Karbasian [0000-0003-2494-6231] | en |
| Orcid | Seyedeh Mahsan Hoseinialfatemi [0000-0002-8293-934X] | en |
| Orcid | Roxana Mansour Ghanaie [0000-0001-7475-0240] | en |
| Orcid | Sedigheh Rafiei Tabatabaei [0000-0003-1723-9424] | en |
| Orcid | Seyed Alireza Fahimzad [0000-0001-6054-0656] | en |
| Orcid | Maryam Rajabnejad [0000-0003-3228-2922] | en |
| Orcid | Farid Imanzadeh [0000-0003-0223-6431] | en |
| Orcid | Abdollah Karimi [0000-0002-4225-0097] | en |
| Orcid | Peyman Eshghi [0000-0002-3503-1363] | en |
| Issued Date | 2020-09-30 | en |
| Abstract | Background: In December 2019, a new coronavirus appeared in China, as a cause of acute respiratory disease. Healthcare Workers (HCWs) in children's hospitals are one of the groups who are at a high rate of exposure to COVID-19 patients. The detection of antibodies is useful and helps diagnose late or recent SARS-CoV-2 infection. Most children may present with asymptomatic or mild SARS-CoV-2 infection and can be silent sources of infection in the community and hospitals. Objectives: This study was conducted to determine the antibodies (IgM and IgG) against SARS-CoV-2 in Mofid children's hospital staff. Methods: This cross-sectional study evaluated 475 staff from Mofid children's hospital from April 20 to May 5, 2020, in Tehran. We collected blood samples for the antibody assay with a rapid test kit. A questionnaire was used to collect demographic and clinical data. Results: Of 475 staff who participated in this study, 25 (5.3%) were diagnosed with COVID-19 by Polymerase Chain Reaction (PCR) and/or CT scan. Besides, 140 (29.4%) of them were positive for IgM and/or IgG SARS-CoV-2 antibodies. Conclusions: The seropositivity of antibodies against SARS-CoV-2 among children's hospital staff was higher than expected. Approximately 5% of the participants were diagnosed as definitive positive COVID-19 cases by PCR and/or CT scan, but 29.4% of them were seropositive. The difference is a warning, as it shows seropositive people could be silent sources of transmission during asymptomatic infection. | en |
| DOI | https://doi.org/10.5812/jjm.108592 | en |
| Keyword | SARS-CoV-2 | en |
| Keyword | COVID-19 | en |
| Keyword | Antibodies | en |
| Keyword | Seroprevalence | en |
| Keyword | Healthcare Workers | en |
| Publisher | Brieflands | en |
| Title | Prevalence of SARS-CoV-2 Specific Antibodies in the Staff of a Children's Hospital, in Tehran, Iran | en |
| Type | Research Article | en |
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