Frequency of Coronavirus NL63 Infection in Children with Upper Respiratory Infection by Real-Time PCR
| Author | Mahtab Mohammadi | en |
| Author | Seyed Ali Mohammad Arabzadeh | en |
| Author | Hamid Reza Mollaei | en |
| Author | Seyed Hamidreza Monavari | en |
| Author | Najmeh Nikpour | en |
| Orcid | Hamid Reza Mollaei [0000-0001-6874-0011] | en |
| Orcid | Seyed Hamidreza Monavari [0000-0003-1517-6036] | en |
| Issued Date | 2020-05-27 | en |
| Abstract | Background: Human coronavirus NL63 (HCoV-NL63) is a new respiratory virus associated with acute respiratory infection in children. Infection with this virus is usually accompanied by upper and lower infections of the respiratory tract in adults. Objectives: In a retrospective study, we investigated the incidence of coronavirus infection in children under the age of five years. Methods: We collected 138 specimens (nasal and throat swabs) from children less than five-years-old with acute respiratory infection from October 2018 to December 2019. Then, HCoV-NL63 was investigated using real-time PCR. Results: Out of 138 samples, 33 (23.9%) were positive for coronavirus NL63, including 21 (63.6%) male samples and 12 (36.4%) female samples. There was no significant correlation between gender and positivity for coronavirus infection (P > 0.05). However, the association of clinical symptoms with the virus was statistically significant (P < 0.05). Conclusions: This study was conducted for the first time in Kerman Province. In this study, the frequency of coronavirus NL63 was evaluated among children with acute respiratory infection with a highly sensitive method, real-time PCR. The prevalence of this virus was 33%, which was more frequent than in similar studies. | en |
| DOI | https://doi.org/10.5812/ijp.101905 | en |
| URI | https://brieflands.com/journals/ijp/articles/101905 | en |
| Keyword | Coronavirus | en |
| Keyword | NL63 | en |
| Keyword | Respiratory Infection | en |
| Keyword | Children | en |
| Keyword | Iran | en |
| Publisher | Brieflands | en |
| Title | Frequency of Coronavirus NL63 Infection in Children with Upper Respiratory Infection by Real-Time PCR | en |
| Type | Research Article | en |
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