Antioxidant effect of extract of the grape seed in streptozotocin induced diabetic rats

Abstract

Background: Diabetes mellitus is a metabolic disorder as old as mankind and its incidence is considered to be high all over the world. Oxidative stress is strongly associated with development and the complications of diabetes. Antioxidant agents, especially with the origin of plants, are of more importance in the treatment of diabetic complications. The main objective of the present study was to evaluate the effect of extract of the grape seed on antioxidants status in streptozotocin induced diabetic rats.