The comparison of titer of Helicobacter Pylori antibody in patients with gastric carcinoma and control group in Zahedan
| Author | SK Nezam | en |
| Author | H Rahimi | en |
| Issued Date | 2005-12-31 | en |
| Abstract | Background: Gastric cancer is the second most common cause of cancer related death in the world. Helicobacter pylori infection is associated with chronic gastritis, a known precursor of gastric cancer. Carcinomas have been shown to be related to a high prevalence of H.Pylori infection. We study titer of H.Pylori antibody in patients with gastric cancer and in patients with non-ulcer dyspepsia. Methods and Materials: During an eleven-month course (October 2001- September 2002) we studied the relation between H. Pylori infection and gastric carcinoma in a case - control study in Zahedan hospitals. The subjects divided into two groups; 40 control subjects and 40 patients with gastric carcinoma. IgG Antibody to H. Pylori was checked in serum of patients in both groups by ELISA method. Results: Each group comprised of 21 male (52.5%) and 19 female (47.5%). Mean age was 53.18 and 56.58 years in control and case group, respectively. Anti-H. Pylori IgG was positive in 100% of patients with gastric carcinoma but only in 28% of the control subjects. Chi-test demonstrated a significant correlation between gastric cancer and Antibody test. (P= 0.000). Patients with gastric carcinoma had higher titer of IgG 85.67 in contrast to those who did not have cancer. Conclusions: Like other epidemiologic studies this study revealed that H. pylori infection is associated with an increased risk of gastric carcinoma and is considered as a cofactor in the pathogenesis of this malignant condition. | en |
| DOI | https://doi.org/ | en |
| URI | https://brieflands.com/journals/zjrms/articles/94922 | en |
| Keyword | Helicobacter Pylori | en |
| Keyword | Gastric cancer | en |
| Keyword | Chronic gastritis | en |
| Publisher | Brieflands | en |
| Title | The comparison of titer of Helicobacter Pylori antibody in patients with gastric carcinoma and control group in Zahedan | en |
| Type | Research Article | en |
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