Penile Metastasis Originating from Prostate Adenocarcinoma: An Unusual Presentation with Penile Curvature

Abstract

Despite the high rate of prostate cancer, the incidence of penile metastasis originating from prostate cancer is extremely rare, especially in the form of Peyronie’s disease. Moreover, brain metastasis, which is caused by prostate cancer, is not a common phenomenon and occurs mostly in older patients. Herein, we report a case of a middle-aged man with penile and brain metastasis originating from prostate cancer. The patient was presented with signs and symptoms of Peyronie’s disease without a significant increase in prostate specific antigen (PSA). The final pathological result was prostate adenocarcinoma with a Gleason score of 5 + 5 = 10 and neuroendocrine features.