Pulmonary Complications in Children After Cardiac Surgery and Its Relationship to Neutrophil-Lymphocyte Ratio: A Retrospective Study
| Author | Neda Entezari Farahabadi | en |
| Author | Behdad Gharib | en |
| Author | Enayatollah Noori | en |
| Author | Sara Memarian | en |
| Author | Mohammadreza Mirzaaghayan | en |
| Orcid | Neda Entezari Farahabadi [0009-0002-4418-9565] | en |
| Orcid | Behdad Gharib [0000-0001-6181-9587] | en |
| Orcid | Enayatollah Noori [0000-0002-4457-129X] | en |
| Orcid | Sara Memarian [0000-0002-3534-0094] | en |
| Orcid | Mohammadreza Mirzaaghayan [0000-0002-7833-9173] | en |
| Issued Date | 2025-12-31 | en |
| Abstract | Background: This study aimed to investigate the incidence and predisposing factors of pulmonary complications in pediatric patients undergoing cardiac surgery and its relationship with the neutrophil-to-lymphocyte ratio (NLR) in the open-heart surgery intensive care unit (ICU-OH) of the Children’s Medical Center Hospital (CMC) in Tehran, Iran. Methods: In this retrospective cohort study, 457 children who underwent open-heart surgery and were transferred to ICU-OH postoperatively were included. Data on age, gender, weight, hospital stay, and risk adjustment for congenital heart surgery (RACHS-1) scores were collected. The incidence of pulmonary complications and its association with NLR were analyzed. Results: The RACHS-1 risk category distribution: Category 1 (15%, n = 65), category 2 (54%, n = 232), category 3 (23%, n = 99), and category 4 (8%, n = 34). Pulmonary complications occurred in 68 children (15.8%), with the highest incidence in infants under one month (34%, n = 18; P < 0.001). Postoperative NLR levels were significantly higher than preoperative levels and were elevated in patients without pulmonary complications, suggesting NLR as a potential predictive factor. Conclusions: The NLR may serve as a useful biomarker for predicting pulmonary complications in pediatric cardiac surgery patients. Further studies are needed to validate these findings and explore underlying mechanisms. | en |
| DOI | https://doi.org/10.5812/icrj-159936 | en |
| Keyword | Congenital Heart Defect | en |
| Keyword | Pulmonary Complications | en |
| Keyword | Neutrophil-to-Lymphocyte Ratio | en |
| Keyword | Intensive Care Unit | en |
| Publisher | Brieflands | en |
| Title | Pulmonary Complications in Children After Cardiac Surgery and Its Relationship to Neutrophil-Lymphocyte Ratio: A Retrospective Study | en |
| Type | Research Article | en |
Files
Original bundle
1 - 1 of 1
Loading...
- Name:
- ircrj-19-1-159936-publish-pdf.pdf
- Size:
- 229.97 KB
- Format:
- Adobe Portable Document Format
- Description:
- Article/s PDF