Dichlorvos Induced Autoimmune Hepatitis: A Case Report and Review of Literature
| Author | Su Xian Zhao | en |
| Author | Qing Shan Zhang | en |
| Author | Li Kong | en |
| Author | Yu Guo Zhang | en |
| Author | Rong Qi Wang | en |
| Author | Yue Min Nan | en |
| Author | Ling Bo Kong | en |
| Issued Date | 2015-05-01 | en |
| Abstract | Introduction: Drug-induced liver injury is a frequent cause of hepatic dysfunction. Several drugs have been identified to cause autoimmune hepatitis (AIH). Environmental chemicals are capable of triggering a certain degree of liver injury. However, toxin induced AIH is rare. Case Presentation: We reported a woman with chronic (long-term) exposures to dichlorvos, which resulted in liver injury and cirrhosis. She was diagnosed after a second liver biopsy, which was correlated with laboratory findings. At the same time, she experienced hepatic cortical blindness during her first admission. Conclusions: Chronic (long-term) exposures to dichlorvos can lead to AIH. A detailed inquiry of medical history and liver biopsy are necessary for the diagnosis of toxin-induced AIH. Corticosteroid therapy is associated with favorable evolution. | en |
| DOI | https://doi.org/10.5812/hepatmon.25469 | en |
| Keyword | Dichlorvos | en |
| Keyword | Autoimmune Hepatitis | en |
| Keyword | Drug-Induced Liver Injury | en |
| Publisher | Brieflands | en |
| Title | Dichlorvos Induced Autoimmune Hepatitis: A Case Report and Review of Literature | en |
| Type | Case Report | en |
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