Association between Immunohistochemical profile and Clinicopathological appearance in Breast Cancer : A 7 year review from Mahdieh Radiotherapy Center, Hamadan, Iran

AuthorKamal Mohammadianen
AuthorAbdolazim Sedighi Pashakien
AuthorEhsan Akbari Hameden
AuthorSepideh Behnooden
AuthorMohammad Abbasien
AuthorMohammad Babaeien
AuthorAfsaneh Madah Safaeeen
AuthorTayebeh Torkamanen
Issued Date2013-12-01en
AbstractIntroduction: Invasive breast cancer is the most common carcinoma in women. Immunohistochemistry classification now plays a key role in prognostic identification and prediction of outcome in this disease. Based on recent gene expression studies, immunohistochemical subtypes are as follows: Luminal A (ER+ and /or PR+, HER2-), luminal B (ER+ and /or PR+, HER2+), HER2+/ ER-, PR-, and basal-like (ER-, PR-, HER2-). These molecular differences have been shown to correlate with clinical features, such as survival, and sensitivity to treatment. In this study we evaluated the association between different subtypes with histological type, grade, tumor stage, lymph node positive ratio, lymph node status, recurrence, and survival.en
DOIhttps://doi.org/en
KeywordBreast Canceren
Keywordchemotherapyen
Keywordsurvivalen
KeywordImmunohistochemistryen
KeywordIHCen
PublisherBrieflandsen
TitleAssociation between Immunohistochemical profile and Clinicopathological appearance in Breast Cancer : A 7 year review from Mahdieh Radiotherapy Center, Hamadan, Iranen
TypeResearch Articleen

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