Efficacy and safety of Oxcarbazepine versus Phenytoin in controlling post stroke seizures in the elderly

Issued Date	2012-06-30	en
Abstract	Background: The prevalence of epilepsy in the elderly is more than other age groups and treatment of epilepsy in this group is challenging for neurologists. The purpose of this study is to compare the efficacy and safety of phenytoin versus oxcarbazepine in the elderly patients with newly diagnosed secondary generalized seizure. Material and methods: We enrolled 142 elderly patients with epilepsy after considering the measures of exclusion and inclusion criteria. The patients were divided in two groups (A&B) randomly. For the group A phenytoin capsule ( >70 y/o 100mg BID & Results: In group A 91.5% of the patients ( n=54) were seizure free in the period of 6 months and in the group B 86.6% of the patients ( n=58) were seizure free ( p=0.377). The frequency of adverse effects was 18.2% in the group A (n=12) and in the group B 6.5% ( n=4) of the patients had adverse effects ( p=0.045).	en
DOI	https://doi.org/	en
Publisher	Brieflands	en
Title	Efficacy and safety of Oxcarbazepine versus Phenytoin in controlling post stroke seizures in the elderly	en
Type	Research Article	en

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