Cardioprotective effect of fasting on ischemia reperfused rat heart after diazepam administration

Abstract

Background: Fasting and calorie restriction have some cardioprotective effects. In view of the effect of fasting on peripheral benzodiazepine receptors and widespread administration of benzodiazepines in medicine, the present study was designed to evaluate whether fasting may affect myocardial vulnerability to cardiac ischemia–reperfusion (I/R) following repeated diazepam administration.