Comparison of f issure s ealant m icroleakage after d epositing on t ooth in i solated and non i solated s tate (in v itro)
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Background: Many clinical studies have shown the efficacy of pit and fissure sealants in reduction of caries. However saliva contamination during the treatment is the cause of fissure sealant failure. The purpose of this study was to evaluate the microleakage of fissure sealant applied under isolated and non-isolated conditions.