Biochemical markers Troponin I, Leptin and CK-MB in coronary artery diseases

Abstract

Background: In recent years, troponin I has been a prognostic factor of myocardial cell injury. Also, regarding the importance of leptin measurement in coronary artery disease investigations are being performed. In addition, CK-MB has been a "gold standard" test for this disease. Objective: The aim of this study was to assess the biochemical markers Troponin I, Leptin and CK-MB in coronary artery diseases. Methods: This was a study on 100 patients who suffered from coronary artery disease. Following blood collection, the serum sample was tested to determine the concentration of troponin I, Leptin, and CK-MB. Troponin I level was measured by two-site immunoluminometric assay. Leptin and CK-MB levels were detected by ELISA. Statistical t-test was employed to analyze the data. Findings: The data obtained in the present study was indicative of a significant correlation between troponin I and Leptin among the patients (p=0.01). Also, a significant relationship was observed between troponin I and CK-MB in our study population (p=0.01). In addition, there was a significant relationship between both leptin and troponin 1 and the gender (p