Association of Metabolic Syndrome and Its Components with Survival of Older Adults
| Author | Ali Bijani | en |
| Author | Seyed Reza Hosseini | en |
| Author | Reza Ghadimi | en |
| Author | Simin Mouodi | en |
| Orcid | Ali Bijani [0000-0003-2233-8726] | en |
| Orcid | Seyed Reza Hosseini [0000-0003-1440-3022] | en |
| Orcid | Reza Ghadimi [0000-0002-4296-2836] | en |
| Orcid | Simin Mouodi [0000-0001-7868-9360] | en |
| Issued Date | 2020-01-31 | en |
| Abstract | Background: Metabolic syndrome (MetS) as an important risk factor arising from insulin resistance accompanying abnormal adipose deposition and function has become a major challenge to public health around the world. Objectives: This research was conducted to evaluate the association of MetS and its components with survival of older adults. Methods: This prospective study is a part of the Amirkola Health and Ageing Cohort Project (2011 - 2017) conducted among 1562 older adults (aged 60 years and over) living in Amirkola, north of Iran. MetS was defined according to four sets of definition: Iranian definition, International Diabetes Federation (IDF) definition, 2001 Adult Treatment Panel (ATP) III and 2005 Adult Treatment Panel (ATP) III. Results: Eight hundred sixty-three (55.2%) males and 699 (44.8%) females with a mean age of 69.3 ± 7.4 years were included in the research. The results showed that 71.9%, 74.3%, 68.8% and 66.7% of older adults had MetS based on 2005 ATP III, Iranian, IDF and 2001 ATP III diagnostic criteria, respectively. Only raised fasting plasma glucose (FPG) had a significant association with a five-year survival rate of older adults (FPG ≥ 110mg/dL: adjusted HR: 2.05; 95% CI: 1.51 - 2.78; P < 0.001). Other MetS components did not show any significant associations with survival (P > 0.05). Nevertheless, MetS itself significantly decreased the survival rate of older adults after adjusting age, gender and number of chronic diseases (HR = 1.67; 95% CI: 1.16 - 2.41; P = 0.006). Conclusions: MetS and one of its components, high FPG, have significant associations with survival of older adults. | en |
| DOI | https://doi.org/10.5812/ijem.91837 | en |
| Keyword | Age | en |
| Keyword | Metabolic Syndrome | en |
| Keyword | Survival | en |
| Publisher | Brieflands | en |
| Title | Association of Metabolic Syndrome and Its Components with Survival of Older Adults | en |
| Type | Research Article | en |
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