The effect of β-ionone on telomerase activity in the human leukemia cell line K562
| Author | Zohreh Faezizadeh | en |
| Author | Amir Gharib | en |
| Author | Masoud Goudarzi | en |
| Issued Date | 2015-07-20 | en |
| Abstract | Background: Telomerase is highly activated in most human cancer cells, therefore, its inhibition has been proposed as a novel and promising strategy for cancer therapy. Many plant-derived anticancer agents act through inhibition of telomerase activity and induction of apoptosis. β-ionone, a carotenoid compound isolated from Roseaceae, has been reported to possess anticancer properties. The present study was undertaken to examine the mechanism of β-ionone-induced apoptosis in human leukemia cell line K562 with special emphasis on its role in telomerase inhibition. | en |
| DOI | https://doi.org/10.22110/jkums.v19i3.2160 | en |
| Keyword | human leukemia | en |
| Keyword | β-ionone | en |
| Keyword | telomerase inhibitors | en |
| Keyword | apoptosis | en |
| Publisher | Brieflands | en |
| Title | The effect of β-ionone on telomerase activity in the human leukemia cell line K562 | en |
| Type | Research Article | en |
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