Testosterone Improved Hyperalgesia in a Patient Under Methadone Maintenance Treatment
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Date
2022-01-31
0000-0002-4313-0214 Journal Title
Journal ISSN
Volume Title
Publisher
Brieflands
Abstract
Introduction: Long-term use of narcotics causes hyperalgesia in some patients with an unknown mechanism known as opioid-induced hyperalgesia (OIH). Case Presentation: Testosterone was prescribed to a 43-year-old man suffering from the effects of OIH syndrome due to long-term use of methadone. Testosterone prescription significantly reduced the hyperalgesia. Conclusions: Testosterone may have a therapeutic value in OIH.