Testosterone Improved Hyperalgesia in a Patient Under Methadone Maintenance Treatment

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AuthorNader Charkhgard
AuthorShahram Naderi
AuthorKamyar Ghani
AuthorMahboubeh Manouchehrabadi
Issued Date2022-01-31
AbstractIntroduction: Long-term use of narcotics causes hyperalgesia in some patients with an unknown mechanism known as opioid-induced hyperalgesia (OIH). Case Presentation: Testosterone was prescribed to a 43-year-old man suffering from the effects of OIH syndrome due to long-term use of methadone. Testosterone prescription significantly reduced the hyperalgesia. Conclusions: Testosterone may have a therapeutic value in OIH.
DOIhttps://doi.org/10.5812/ans.121361
KeywordOpioid
KeywordHyperalgesia
KeywordTestosterone
PublisherBrieflands
TitleTestosterone Improved Hyperalgesia in a Patient Under Methadone Maintenance Treatment
TypeCase Report
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