Summary on the Seroprevalence of Hepatitis C Among Patients with Hodgkin’s Lymphoma, an Implication for Risk by Metanalysis.

Abstract

Hepatitis C virus (HCV) infection is an increasing problem, with millions people all over the world being infected. It is accepted as a significant public health problem with several life altering complications, especially hepatocellular carcinoma. The correlation between HCV infection and non – Hodgkin’s lymphoma is no doubt at present. However, the reports on the correlation between HCV infection and Hodgkin’s lymphoma are still controversy. The correlation between this virus infection and development of Hodgkin’s lymphoma is of interest. Here, the author performs an appraisal on the seroprevalence of HCV among patients with Hodgkin’s lymphoma comparing with healthy control subjects. Risk analysis was performed. According to the literature review, 3 reports were recruited. According to the metanalysis, 184 cases and 904 healthy subjects were investigated for HCV seroprevalence. The overall Anti HCV seropositive rate in the patients (3/184) and healthy subjects (6/904) are 1.6 % and 0.7 %, respectively. The odds ratio is 2.5. According to this study, it could be seen that having Anti HCV seropositive is a weak risk for Hodgkin’s lymphoma.