Latent Autoimmune Diabetes of Adults in Latakia, Syria
| Author | AA Al-Farwi |
| Author | MI Khayat |
| Author | M Muhsen Al-Mehri |
| Issued Date | 2010-01-31 |
| Abstract | This study aimed at assessing the frequency of latent autoimmune diabetes of adults (LADA) and its laboratory and clinical characteristics at the Diabetic Center of Latakia, Syria. Materials and Methods: Based on glutamic acid decarboxylase autoantibodies positivity, a population of 254 type 2 diabetic males and females, aged 35 to 75 years, were subdivided and studied in terms of the laboratory and clinical characteristics. Results: Glutamic acid decarboxylase autoantibodies (GADAs) were positive (GADA+) in 45 diabetic patients versus 209 type 2 diabetics with GADA negative (GADA-). In both subgroups, GADA+ and GADA-, no significant differences were observed in terms of anthropometric and clinical features except for body mass index (BMI) which was significantly lower in GADA+ subgroup (27.6±4.8 vs. 29.8±5.9; P= 0.02). Significant poor glycemic control was detected in terms of fasting blood sugar (FBS) (221.6±77.9 vs 182±66.7; P=0.001), glucosuria (60% vs. 41.6%; P=0.025), and ketonuria (22.2% vs. 3.8%; P50 IU/ml) presented significantly low BMI (P=0.012) and c-peptide levels (P |
| DOI | https://doi.org/ |
| Keyword | LADA |
| Keyword | Type 2 diabetes |
| Keyword | GADA |
| Keyword | Cpeptide |
| Keyword | BMI |
| Publisher | Brieflands |
| Title | Latent Autoimmune Diabetes of Adults in Latakia, Syria |
| Type | Research Article |
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