Latent Autoimmune Diabetes of Adults in Latakia, Syria

AuthorAA Al-Farwien
AuthorMI Khayaten
AuthorM Muhsen Al-Mehrien
Issued Date2010-01-31en
AbstractThis study aimed at assessing the frequency of latent autoimmune diabetes of adults (LADA) and its laboratory and clinical characteristics at the Diabetic Center of Latakia, Syria. Materials and Methods: Based on glutamic acid decarboxylase autoantibodies positivity, a population of 254 type 2 diabetic males and females, aged 35 to 75 years, were subdivided and studied in terms of the laboratory and clinical characteristics. Results: Glutamic acid decarboxylase autoantibodies (GADAs) were positive (GADA+) in 45 diabetic patients versus 209 type 2 diabetics with GADA negative (GADA-). In both subgroups, GADA+ and GADA-, no significant differences were observed in terms of anthropometric and clinical features except for body mass index (BMI) which was significantly lower in GADA+ subgroup (27.6±4.8 vs. 29.8±5.9; P= 0.02). Significant poor glycemic control was detected in terms of fasting blood sugar (FBS) (221.6±77.9 vs 182±66.7; P=0.001), glucosuria (60% vs. 41.6%; P=0.025), and ketonuria (22.2% vs. 3.8%; P50 IU/ml) presented significantly low BMI (P=0.012) and c-peptide levels (Pen
DOIhttps://doi.org/en
KeywordLADAen
KeywordType 2 diabetesen
KeywordGADAen
KeywordCpeptideen
KeywordBMIen
PublisherBrieflandsen
TitleLatent Autoimmune Diabetes of Adults in Latakia, Syriaen
TypeResearch Articleen

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