Effects of Anesthetic Management on Inflammatory Markers in Patients After Major Abdominal Surgeries: A Double-Blind Controlled Study
| Author | Esam Hamed | en |
| Author | Nagla El-Melegy | en |
| Author | Samir Ammar | en |
| Author | rasha hamed | en |
| Issued Date | 2022-09-30 | en |
| Abstract | Background: Surgical trauma induces systemic inflammatory responses. We aimed to evaluate the influence of different analgesic models on postoperative pain and inflammatory markers modulation after major abdominal surgeries. Materials and Methods: A total of 105 patients scheduled for elective abdominal colorectal surgeries were selected and randomly assigned to one of the three groups: Group-1 (GM) four micrograms/kg of IT morphine; Group-2 (GML) four microgram/kg of IT morphine plus 1.5 mg/kg intravenous Lidocaine loading dose and 2 mg/min saline infusion during the operation and the next 4 hours postoperative; Group-3 (G0, control group) no added drugs. Results: Pain scored statistically significant lower figures in GML than the other two groups; p | en |
| DOI | https://doi.org/10.22037/jcma.v7i3.38005 | en |
| Keyword | Keywords: Abdominal surgeries | en |
| Keyword | Postoperative pain | en |
| Keyword | TNF-alpha and TGF-beta | en |
| Publisher | Brieflands | en |
| Title | Effects of Anesthetic Management on Inflammatory Markers in Patients After Major Abdominal Surgeries: A Double-Blind Controlled Study | en |
| Type | Original Articles | en |