Utilization of Magnesium for the Treatment of Chronic Pain
| Author | Ivan Urits | en |
| Author | Jai Won Jung | en |
| Author | Ariunzaya Amgalan | en |
| Author | Luc Fortier | en |
| Author | Anthony Anya | en |
| Author | Brendan Wesp | en |
| Author | Vwaire Orhurhu | en |
| Author | Elyse M Cornett | en |
| Author | Alan D. Kaye | en |
| Author | Farnad Imani | en |
| Author | Giustino Varrassi | en |
| Author | Henry Liu | en |
| Author | Omar Viswanath | en |
| Orcid | Ivan Urits [0000-0002-3652-6085] | en |
| Orcid | Luc Fortier [0000-0001-9125-1371] | en |
| Orcid | Elyse M Cornett [0000-0001-7961-3931] | en |
| Orcid | Alan D. Kaye [0000-0003-2464-0187] | en |
| Orcid | Farnad Imani [0000-0003-0814-0772] | en |
| Orcid | Giustino Varrassi [0000-0002-3822-2923] | en |
| Orcid | Omar Viswanath [0000-0002-6124-7037] | en |
| Issued Date | 2021-02-06 | en |
| Abstract | Context: The International Association for the Study of Pain (IASP) defines chronic pain as pain that persists or recurs for longer than 3 months. Chronic pain has a significant global disease burden with profound effects on health, quality of life, and socioeconomic costs. Evidence Acquisition: Narrative review. Results: There are several treatment options, including pharmacological therapy, physical rehabilitation, psychological therapies, and surgical interventions, for chronic pain management. Magnesium has been FDA-approved for several indications including hypomagnesemia, arrhythmia, prevention of seizures in eclampsia/preeclampsia, and constipation. Magnesium has been used for numerous off-label uses, notably for acute and chronic pain management. The mechanism of magnesium in pain management is primarily through its action as a voltage-gated antagonist of NMDA receptors, which are involved in pain transduction. Conclusions: This narrative review will focus on the current evidence and data surrounding the utilization of magnesium as a treatment option for chronic pain. | en |
| DOI | https://doi.org/10.5812/aapm.112348 | en |
| Keyword | Chronic Pain | en |
| Keyword | Infusion | en |
| Keyword | Intravenous | en |
| Keyword | Magnesium Sulfate | en |
| Keyword | Chronic Regional Pain Syndrome | en |
| Keyword | Peripheral Neuropathy | en |
| Keyword | Abdominal Pain | en |
| Publisher | Brieflands | en |
| Title | Utilization of Magnesium for the Treatment of Chronic Pain | en |
| Type | Review Article | en |
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