Frequency of Infectious Agents After Bone Marrow Transplantation in Various Regions of Iran (2001 - 2017): A Systematic Review

AuthorMandana Afsharianen
AuthorLeila Hamzeloen
AuthorAlireza Janbakhshen
AuthorFeizollah Mansourien
AuthorBabak Sayaden
AuthorSiavash Vazirien
AuthorMohsen Azizien
AuthorMohammad Hossein Zamanianen
AuthorMaede Noorien
OrcidFeizollah Mansouri [0000-0002-5316-3220]en
OrcidBabak Sayad [0000-0001-8686-9986]en
OrcidSiavash Vaziri [0000-0002-3907-6155]en
OrcidMohsen Azizi [0000-0002-3203-5473]en
OrcidMohammad Hossein Zamanian [0000-0002-5459-3695]en
Issued Date2021-12-31en
AbstractContext: Infections are a major cause of disease and mortality in transplant recipients. Despite the studies conducted in Iran, no comprehensive and general research is available in this area. The present study aimed to determine the frequency of infectious agents in patients after bone marrow transplantation in Iran. Method: In this systematic review, relevant studies were selected based on type and objective, and data were collected from the articles published in Iran regarding the frequency of infectious agents after bone marrow transplantation in different regions of Iran. The studies were collected using systematic search methods. Results: In total, 11 studies were identified regarding infectious agents after bone marrow transplantation. Six studies were conducted in Tehran, three studies were performed in Shiraz, and Mashhad and Semnan provinces were the locations of two separate studies. Most of the case studies identified viral agents (54.5%; n = 6), followed by fungal infectious agents (27.3%; n = 3) and bacterial agents (18.2%; n = 2). Gram-positive bacteria (bacterial agents), cytomegalovirus (viral agents), and Candida and Aspergillus (fungi) had the highest frequency after bone marrow transplantation. Conclusions: According to the results, viral, fungal, and bacterial infectious agents were respectively most frequent in patients receiving bone marrow transplants. Gram-positive bacteria (bacterial agents), cytomegalovirus (viral agents), and Candida and Aspergillus (fungi) had the highest frequency after bone marrow transplantation.en
DOIhttps://doi.org/10.5812/jkums.114622en
KeywordBone Marrow Transplantationen
KeywordInfectionsen
KeywordSystematic Reviewen
KeywordRegions of Iranen
PublisherBrieflandsen
TitleFrequency of Infectious Agents After Bone Marrow Transplantation in Various Regions of Iran (2001 - 2017): A Systematic Reviewen
TypeReview Articleen

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