Frequency of Infectious Agents After Bone Marrow Transplantation in Various Regions of Iran (2001 - 2017): A Systematic Review

AuthorMandana Afsharian
AuthorLeila Hamzelo
AuthorAlireza Janbakhsh
AuthorFeizollah Mansouri
AuthorBabak Sayad
AuthorSiavash Vaziri
AuthorMohsen Azizi
AuthorMohammad Hossein Zamanian
AuthorMaede Noori
Issued Date2021-12-31
AbstractContext: Infections are a major cause of disease and mortality in transplant recipients. Despite the studies conducted in Iran, no comprehensive and general research is available in this area. The present study aimed to determine the frequency of infectious agents in patients after bone marrow transplantation in Iran. Method: In this systematic review, relevant studies were selected based on type and objective, and data were collected from the articles published in Iran regarding the frequency of infectious agents after bone marrow transplantation in different regions of Iran. The studies were collected using systematic search methods. Results: In total, 11 studies were identified regarding infectious agents after bone marrow transplantation. Six studies were conducted in Tehran, three studies were performed in Shiraz, and Mashhad and Semnan provinces were the locations of two separate studies. Most of the case studies identified viral agents (54.5%; n = 6), followed by fungal infectious agents (27.3%; n = 3) and bacterial agents (18.2%; n = 2). Gram-positive bacteria (bacterial agents), cytomegalovirus (viral agents), and Candida and Aspergillus (fungi) had the highest frequency after bone marrow transplantation. Conclusions: According to the results, viral, fungal, and bacterial infectious agents were respectively most frequent in patients receiving bone marrow transplants. Gram-positive bacteria (bacterial agents), cytomegalovirus (viral agents), and Candida and Aspergillus (fungi) had the highest frequency after bone marrow transplantation.
DOIhttps://doi.org/10.5812/jkums.114622
KeywordBone Marrow Transplantation
KeywordInfections
KeywordSystematic Review
KeywordRegions of Iran
PublisherBrieflands
TitleFrequency of Infectious Agents After Bone Marrow Transplantation in Various Regions of Iran (2001 - 2017): A Systematic Review
TypeReview Article
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