Cystatin C and Neutrophil Gelatin-associated Lipocalin (NGAL) Can Predict Acute Kidney Injury and In-Hospital Mortality in COVID-19 Patients

AuthorSanaa Wasfyen
AuthorEman Wasfeyen
AuthorAshraf Elmaraghyen
AuthorEman AbdelFatahen
AuthorAyman Tharwaten
Issued Date2022-03-31en
AbstractBackground: Prediction and early diagnosis of acute kidney injury (AKI) in critically ill Coronavirus disease 2019 (COVID-19) patients are of great importance. Therefore, using promising renal biomarkers such as cystatin C and neutrophil gelatinase-associated lipocalin (NGAL) to identify the risk of future AKI is crucial. Materials and Methods: A total of 89 adult patients with COVID-19 were included in this study. Serum cystatin C and NGAL concentration were assessed on intensive care unit (ICU) admission then repeated after 48 hours. Serum creatinine was followed for 7 days to report the development of AKI. Results: Among the COVID-19 patients, 28.1% developed AKI. Although admission serum creatinine was not significantly different between the AKI group and the non-AKI group (p=0.375), admission Cystatin C (p=0.018), and NGAL (pen
DOIhttps://doi.org/10.22037/jcma.v7i1.36855en
KeywordCystatin Cen
KeywordNGALen
Keywordacute kidney injuryen
KeywordCOVID-19en
Keywordin-hospital mortalityen
PublisherBrieflandsen
TitleCystatin C and Neutrophil Gelatin-associated Lipocalin (NGAL) Can Predict Acute Kidney Injury and In-Hospital Mortality in COVID-19 Patientsen
TypeOriginal Articlesen

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