Relationship between loss of exercise consequences and risk of cardiovascular diseases after detraining

Abstract

Background: The studies show that regular exercise may play an important role in improvement the cardiovascular status and with detraining period people will loose its useful outcome. The aim of this study was to assess the effect of short detraining period on cardiovascular biomarkers in Wistar rats.Materials and Method: Forty-two male rats were divided randomly in two groups: experimental group (n=24) and control group (n=18). The training program was done 3 times per week, for 8 weeks. Then six rats experienced detraining. The blood samples were collected after 14 fasting hours in different stages and with the same conditions. The quantity of sICAM-1 was measured, using the commercial R&D Elisa kit. The quantity of total cholesterol (TC), triglyceride (TG), HDL & LDL in plasma was measured by using Pars-Azmoon kits. Data were analyzed by Kolmogrov-Smirnov, repeated measures of ANOVA, LSD and t-test. The amount of errors were computed in the level of p