Medroxyprogesterone Acetate and Progesterone, Used Short Term, Do not Adversely Affect Forearm Reactive Hyperemia in Postmenopausal Women on Estradiol Therapy
| Author | MM Cho | en |
| Author | HN Hodis | en |
| Author | WJ Mack | en |
| Author | S Roy | en |
| Author | RJ Paulson | en |
| Author | Y Li | en |
| Author | FZ Stanczyk | en |
| Issued Date | 2008-04-30 | en |
| Abstract | This study aimed at investigating whet-her oral medroxyprogesterone acetate (MPA) or micronized progesterone (P) combined with micronized estradiol (E2) adversely affect endothelial function in postmenopausal women. Materials and Methods: Randomized, double-blind, crossover trial of MPA or micronized P with oral E2 treatment in menopausal women. Result: Flow-mediated, endothelium-dependent vasodilation of the brachial artery was not sig-nificantly affected by short-term administration of E2 alone or E2 combined with cyclic MPA, or E2 combined with cyclic P. Conclusion: Short-term oral E2 treatment of postmenopausal women alone or with cyclic oral MPA or oral P did not affect flow-mediated en-dothelium-dependent vasodilation. | en |
| DOI | https://doi.org/ | en |
| Keyword | Medroxyprogesterone acetate | en |
| Keyword | progesterone | en |
| Keyword | estradiol | en |
| Keyword | forearm reactive hyperemia | en |
| Publisher | Brieflands | en |
| Title | Medroxyprogesterone Acetate and Progesterone, Used Short Term, Do not Adversely Affect Forearm Reactive Hyperemia in Postmenopausal Women on Estradiol Therapy | en |
| Type | Research Article | en |
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