Lessons From the KK-Ay Mouse, a Spontaneous Animal Model for the Treatment of human Type 2 Diabetic Nephropathy
Author | Yasuhiko Tomino | en |
Issued Date | 2012-06-01 | en |
Abstract | Abstract: Diabetic nephropathy is a major cause of end-stage kidney disease (ESKD) in patients with type 1 and type 2 diabetes throughout the world. In human glomeruli, expansion of diffuse mesangial matrices, exudative lesions and/or segmental nodular sclerosis are pathological features of diabetic nephropathy. There have been many reports on the pathogenesis and treatment of type 2 diabetes using various animal models. | en |
DOI | https://doi.org/10.5812/numonthly.1954 | en |
Keyword | Models | en |
Keyword | Animal | en |
Keyword | Therapeutics | en |
Keyword | Diabetic Nephropathies | en |
Publisher | Brieflands | en |
Title | Lessons From the KK-Ay Mouse, a Spontaneous Animal Model for the Treatment of human Type 2 Diabetic Nephropathy | en |
Type | Review Article | en |