Lessons From the KK-Ay Mouse, a Spontaneous Animal Model for the Treatment of human Type 2 Diabetic Nephropathy

AuthorYasuhiko Tominoen
Issued Date2012-06-01en
AbstractAbstract: Diabetic nephropathy is a major cause of end-stage kidney disease (ESKD) in patients with type 1 and type 2 diabetes throughout the world. In human glomeruli, expansion of diffuse mesangial matrices, exudative lesions and/or segmental nodular sclerosis are pathological features of diabetic nephropathy. There have been many reports on the pathogenesis and treatment of type 2 diabetes using various animal models.en
DOIhttps://doi.org/10.5812/numonthly.1954en
KeywordModelsen
KeywordAnimalen
KeywordTherapeuticsen
KeywordDiabetic Nephropathiesen
PublisherBrieflandsen
TitleLessons From the KK-Ay Mouse, a Spontaneous Animal Model for the Treatment of human Type 2 Diabetic Nephropathyen
TypeReview Articleen

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