Demographic Analysis of Patients With Multiple Sclerosis; Individual Variability Related to the Time Interval

Abstract

Background: According to the published articles, there is an increase in the prevalence of MS all over the world. Regarding demographic characteristics for unknown reasons, females are more affected than males. Objectives: The aim of this study was demographic analysis and model of changes in patients for three years in a local teaching hospital in Isfahan/Iran. Patients and Methods: In total, 1500 patients with MS were studied within three Intervals (I) from; 1 - 2011/05/22 to 2012/03/18 called I1, 2- 2012/03/22 to 2013/03/19 called I2 and 3- 2013/03/22 to 2013/10/19 called I3. Data was recorded in Excel and analyzed using SPSS for windows. Results: Of the total population studied, 75% were female. 32% and 33% of patients related to the age groups of 20 - 30 and 30 - 40 years, respectively. However the number of patients related to time interval I3 were 472, but there was an increase in the number of patients studied from I1 to I2 (394 vs. 634). Approximately 13% of total population had MS attack more than 4 to 19 times. Conclusions: In agreement with previous reports, due to unknown reasons, the number of patients in general and the number of females in particular were increased annually. Within this population due to inter- and intra- individual variability, pharmacokinetic studies seem to be valuable.