Proteomics Study of extremely low frequency electromagnetic field (50 Hz) on human neuroblastoma cells

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AuthorHadi Hasanzadehen
AuthorMosatafa Rezaei-Taviranien
AuthorSamaneh Seyyedien
AuthorAlireza Emadien
OrcidMosatafa Rezaei-Tavirani [0000-0003-1767-7475]en
Issued Date2015-12-31en
Abstract  Introduction: Extremely low frequency electromagnetic field (ELF-EMF) is one of common environmental factors in today’s modern life. In recent years, a special interest has been directed toward the possible effects of ELF-EMFs on biological systems. Since the mechanism underlying the ELF-EMFs’ biological effects are still unknown, we decided to conduct an in vitro study to understand the possible mechanisms.   Material and Methods: SH-SY5Y- human neuroblastoma cell line were placed in the EL-EM Field with the intensity of 1 mT and frequency of 50 Hz and for a period of 4 hours/day, in 2 days period. The cell morphology and protein expression were measured by using proteomic methods. Statistical analysis was performed by using Non Linear Spot Progenesis Same software.   Results : Our results showed that ELF-EMF could likely change the cell morphology and proliferation.   Conclusion: Statistical analysis in our study showed that ELF-EMF with a frequency of 50Hz and intensity of 1mT could significantly change the protein expression (P ;le 0.05).  en
DOIhttps://doi.org/en
URIhttps://brieflands.com/journals/koomesh/articles/150796en
KeywordElectromagnetic fieldsen
KeywordProteomicsen
KeywordNeuroblastomaen
Keywordمیدان‌های الکترومغناطیسen
Keyword‌پروتئومیکen
Keywordنوروبلاستومen
PublisherBrieflandsen
TitleProteomics Study of extremely low frequency electromagnetic field (50 Hz) on human neuroblastoma cellsen
TypeResearch Articleen

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