A Study on the Relationship between Serum Beta 2-Microglobulin Levels, Underlying Chronic Kidney Disease, and Peripheral Arterial Disease in High-Vascular-Risk Patients
| Author | Diego Real de Asúa | en |
| Author | Ramón Puchades | en |
| Author | Iluminada García-Polo | en |
| Author | Carmen Suárez | en |
| Issued Date | 2012-12-31 | en |
| Abstract | Background: Serum beta 2-microglobulin (B2M) levels have been found to be increased in patients with peripheral arterial disease (PAD), yet it is still unknown whether B2M correlates with PAD intensity. Objectives: We aim to evaluate the correlation between B2M and the ankle-brachial index (ABI) values in high-vascular-risk patients. Methods: This is a cross-sectional study of 63 high-vascular-risk patients admitted to the Cardiology Department or evaluated as outpatients in the Internal Medicine Department of our institution. Patients were classified into two groups according to their ABI: patients without PAD (n = 44, ABI values between 0.9 and 1.4) and patients with PAD (n = 19, ABI values lower than 0.9 or higher than 1.4). We performed univariate and multivariate analysis based on a multiple linear regression model. Results: Serum B2M levels were higher in patients with pathological ABI values than in those without PAD (2.36 ± 1.13 vs. 1.80 ± 0.65 mg/L; P | en |
| DOI | https://doi.org/ | en |
| Keyword | Ankle-Brachial Index | en |
| Keyword | Beta 2-Microglobulin | en |
| Keyword | Glomerular Filtration Rate | en |
| Keyword | Peripheral Arterial Disease | en |
| Keyword | Renal Insufficiency | en |
| Publisher | Brieflands | en |
| Title | A Study on the Relationship between Serum Beta 2-Microglobulin Levels, Underlying Chronic Kidney Disease, and Peripheral Arterial Disease in High-Vascular-Risk Patients | en |
| Type | Research Article | en |