Early Diagnosis of Acute Coronary Syndrome with Sensitive Troponin I and Ischemia Modified Albumin
| Author | MA Takhshid | en |
| Author | Javad Kojuri | en |
| Author | SMB Tabei | en |
| Author | AR Tavasouli | en |
| Author | S Heidary | en |
| Author | M Tabandeh | en |
| Issued Date | 2010-12-31 | en |
| Abstract | Background: In this study we compared the diagnostic performance of serum ischemia modified albumin (IMA) and sensitive cardiac troponin I (cTnI) assay for the detection of acute coronary syndrome (ACS) in patients presenting to the emergency department (ED) with acute chest pain.Methods: A prospective study was conducted on 123 patients presenting to the ED within three hours of acute chest pain. A 12-lead ECG was recorded and IMA and cTnI were measured on arrival at the ED. After diagnostic testing, the patients were classified as either ACS (n=70) or non- ACS (n= 53). The results of IMA, ECG, and cTnI, alone and in combination, were correlated with final diagnoses.Results: IMA showed higher sensitivity (84%) and negative predictive value (NPV, 88%) compared to cTnI (sensitivity 42%, NPV 66%) and ECG (sensitivity 58%, NPV 74%). Combined use of IMA, cTnI and ECG significantly improved the sensitivity (96%, P | en |
| DOI | https://doi.org/ | en |
| Keyword | Ischemia modified albumin | en |
| Keyword | cardiac troponin | en |
| Keyword | acute coronary syndrome | en |
| Publisher | Shiraz University of Medical Sciences | en |
| Title | Early Diagnosis of Acute Coronary Syndrome with Sensitive Troponin I and Ischemia Modified Albumin | en |
| Type | Research Article | en |
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