Oral Wheat Immunotherapy in a Patient with Anaphylaxis Despite Negative Sensitization Tests

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AuthorMahsa Rekabien
AuthorSaba Arshien
AuthorSepideh Darougaren
AuthorVahab Rekabien
AuthorMohammad Nabavien
AuthorMorteza Fallahpouren
AuthorMohammad Hassan Bemanianen
AuthorAbolfazl Rajabien
OrcidSepideh Darougar [0000-0003-1399-8351]en
OrcidMohammad Nabavi [0000-0001-6558-0390]en
Issued Date2018-12-05en
AbstractIntroduction: Wheat allergy can develop at any stage of life. The aim of this report was to demonstrate that skin testing and specific IgE have poor specificities and sensitivities for wheat allergy. Case Presentation: A 37-year-old female presented symptoms that were initiated immediately after consumption of bread and biscuits. She was well until two months prior to her recent admission. Her skin prick test, RIDA assay, and patch test for wheat showed negative results despite a history of two episodes of anaphylaxis. She underwent an oral food challenge, which confirmed wheat allergy. A desensitization procedure was recommended for her. At the end of the immunotherapy process, she had normal intake of wheat without any symptoms. Conclusions: Negative sIgE and SPT results do not rule out clinical food allergy. Oral food challenges are still the cornerstone of diagnosis of food allergy.en
DOIhttps://doi.org/10.5812/semj.83309en
URIhttps://brieflands.com/journals/semj/articles/83309en
KeywordWheaten
KeywordFood Allergyen
KeywordDesensitizationen
KeywordOral Food Challengeen
KeywordOral Immunotherapyen
PublisherBrieflandsen
TitleOral Wheat Immunotherapy in a Patient with Anaphylaxis Despite Negative Sensitization Testsen
TypeCase Reporten

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