Genomic Investigation of Hepatitis E Virus in Persian Gazelle

AuthorMahnaz Amiri Dehnoyien
AuthorAzam Mokhtarien
OrcidAzam Mokhtari [0000-0003-0139-1456]en
Issued Date2020-12-31en
AbstractBackground: Numerous studies have shown that a variety of animal species can be the hosts of the hepatitis E virus. In addition to pigs, wild boars, deer, and rats, new types of hepatitis E virus have been found in ferrets and bats. Objectives: Due to the limited reports of virus identification in deer and the potential role of this animal as a reservoir in maintaining the virus, in the present study, the genome of the virus was investigated in the samples of feces and gastrointestinal swabs of Gazelle. Methods: Samples were collected from 50 Gazelle in the protected area of Moteh and the lands around Maymeh City from winter, 2017 to winter, 2019. After RNA extraction and reverse transcription reaction, the genomic identification of the virus was performed by RT-PCR. Results: The results of the present study showed that out of 50 samples taken, three samples were positive for the hepatitis E virus, including one sample from female Gazelle under one year of age and two samples from female animals over one year of age. Conclusions: No statistically significant relationship was found between hepatitis E infection, age, and sex using statistical tests. The present study indicated the contamination of Iranian wildlife animals and the importance of these animals as the potential reservoirs of the disease.en
DOIhttps://doi.org/10.5812/jjcmb.111737en
KeywordHepatitis Een
KeywordGazelleen
KeywordGenomic Searchen
KeywordPrevalenceen
PublisherBrieflandsen
TitleGenomic Investigation of Hepatitis E Virus in Persian Gazelleen
TypeResearch Articleen

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