Screening of three common mtDNA mutations among subjects with autosomal recessive non-syndromic hearing loss in Sistan va Baluchestan province, Iran
| Author | Fartemeh Azadegan-Dehkordi | en |
| Author | Mostafa Montazer-Zohouri | en |
| Author | Effat Farrokhi | en |
| Author | S.Abolfateh Shirmardi | en |
| Author | Mojtaba Saedi-Marghmaleki | en |
| Author | Zohreh Ataei | en |
| Author | Somayeh Reisi | en |
| Author | Marzieh Abolhasani | en |
| Author | Hamid Khazraei | en |
| Author | Mohammad T. Akbari | en |
| Author | Morteza Hashemzadeh | en |
| Issued Date | 2011-10-31 | en |
| Abstract | Background: Non-syndromic hearing loss may be induced by mutations in both nuclear and mitochondrial genes. Mutations in mtDNA are present in less than 1% of the children with pre-lingual deafness but are more prevalent later. Most of the molecular defects responsible for mitochondrial disorder, associated with hearing loss may be induced by mutations in the 12SrRNA and tRNA genes. This aim of this study was to investigate the frequency of three common mtDNA mutations including A1555G, A3243G and A7445G in a cohort of autosomal recessive non-syndromic hearing loss (ARNSHL) subjects in Sistan va Baluchestan province. | en |
| DOI | https://doi.org/ | en |
| Keyword | ARNSHL | en |
| Keyword | mtDNA mutations | en |
| Keyword | A1555G | en |
| Keyword | A3243G | en |
| Keyword | A7445G | en |
| Publisher | Brieflands | en |
| Title | Screening of three common mtDNA mutations among subjects with autosomal recessive non-syndromic hearing loss in Sistan va Baluchestan province, Iran | en |
| Type | Research Article | en |
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