Various types of glomerulonephritis in children in south Iran

Abstract

Background: Acute glomrulonephritis is a common renal disease in children. It can be primary disease or secondary to systemic diseases. Various forms of glumerulonephritis have different prevalence and prognosis in each region. The present study was designed for evaluation of prevalence of various types of glomerulonephritis in Iranian children, their prognosis and related factors. Methods and Materials: This study was done on 140 children with diagnosis of glomerulonephritis between 1981-2002. Data about their types of glomerulonephritis, prognosis and presentation were obtained by referring to patient’s files. Results: The patients were aged 2-18 years and girls were more. The most common type of glomerulonaphritis was lupus nephritis (34.28%) that followed by MPGN (24.28%). Twenty percent of patients was recovered, 19.2% hypertensive, 31.44% chronic renal failure and 5.7% dead. The most related factors were severe proteinuria, type of glomerulonephritis, sonography finding. Mean renal and patient survival was 56.6±3.09 and 90.09±4.4 months respectively. Conclusions: In evaluation of children with glomerulonephritis, we must consider prevalence of various types of glomerulonephritis in the region and factors related to prognosis. It also is important that prognosis is related to more than one factor.