Low-Dose Ketamine Infusion Versus Morphine Infusion During Abdominoplasty to Change the Postoperative Pain Profile

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AuthorHassan Alien
AuthorAhmed Abdelaziz Ismailen
AuthorAmr Samir Wahdanen
OrcidHassan Ali [0000-0001-8272-3031]en
OrcidAhmed Abdelaziz Ismail [0000-0003-0155-004X]en
Issued Date2020-12-19en
AbstractBackground: With the increased number of abdominoplasty all over the world, and the need to manage postoperative pain, it is a must to find proper and effective drugs to decrease opioid consumption in the postoperative period. Objectives: In this double-blind randomized controlled clinical trial, we assumed that low-dose ketamine infusion will reduce the postoperative pain profile than the conventional method of morphine. Methods: The scheduled patients for abdominoplasty under general anesthesia were recruited in two groups: group (K) with low-dose ketamine infusion intra-operatively (80 patients) and group (M) with morphine infusion intra-operatively (80 patients). Both groups were monitored intraoperatively and postoperatively for rescue doses of fentanyl, visual analogue scale (VAS), and side effects. Results: There were no statistical differences between both groups regarding the fentanyl rescue doses intra- and postoperative with no remarkable side effects. Conclusions: Low-dose ketamine has a useful analgesic effect in abdominoplasty similar to morphine without remarkable side effects, such as sedation or hallucinations.en
DOIhttps://doi.org/10.5812/aapm.108469en
KeywordKetamineen
KeywordMorphineen
KeywordAbdominoplastyen
KeywordPainen
PublisherBrieflandsen
TitleLow-Dose Ketamine Infusion Versus Morphine Infusion During Abdominoplasty to Change the Postoperative Pain Profileen
TypeResearch Articleen

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