Randomized Control Trial Using Ropivacaine in Spinal Anaesthesia With and Without Intravenous Dexmedetomidine in Lower Limb Surgeries

Abstract

Background: hyperbaric bupivacaine is commonly used in regional anesthesia, especially for the subarachnoid blockade. Several studies demonstrated the efficacy of ropivacaine in different regional anesthesia techniques. Dexmedetomidine has been studied and shown to have synergism local anesthetics. In this study, we aimed to find the efficacy of dexmedetomidine in improving the analgesia quality and duration of the subarachnoid blockade in our hospital scenario. Materials and Methods: One hundred adult patients were divided into two groups of 50 each. Group A received 3 mL of 0.5% isobaric ropivacaine. Group B received 3 mL 0.5% isobaric ropivacaine was used for spinal anesthesia followed by a loading dose of IV dexmedetomidine. Group A received isotonic saline infusion. Results: The duration of the motor block in group A was 139.38?21.22 minutes vs.179.13?31.18 minutes in group B (P