Molecular Aspects of Glucose-6-Phosphate Dehydrogenase Deficiency in Iran
| Author | Ali Dehghanifard | en |
| Author | Yousef Mortazavi | en |
| Author | Najmaldin Saki | en |
| Author | Majid Farshdusti-Hagh | en |
| Issued Date | 2012-09-30 | en |
| Abstract | Background: G6PD deficiency is the most common hereditary enzyme deficiency that affected more than 400 million people worldwide. This enzyme deficiency is caused by a spectrum of mutations in the gene encoding G6PD on chromosome X. Epidemiologically G6PD deficiency has been specially considered in Middle East countries including Iran, Oman and Saudi Arabia.Materials and Methods: This study has reviewed more than 70 papers related to the epidemiological significance and various diagnostic strategies of G6PD deficiency from 1956 to 2010.Results: The results showed a higher prevalence of Mediterranean variant followed by Chatham and Cosenza compared to other variants in Iran.Conclusion: Accurate identification of G6PD deficiency variants in areas with high prevalence of this disease will help to screen patients and their families with risk level when faced with oxidant agents. | en |
| DOI | https://doi.org/ | en |
| Keyword | Glucose-6-phosphate | en |
| Keyword | dehydrogenase | en |
| Keyword | Favism | en |
| Keyword | Mediterranean Variant | en |
| Keyword | Hemolytic anemia | en |
| Publisher | Brieflands | en |
| Title | Molecular Aspects of Glucose-6-Phosphate Dehydrogenase Deficiency in Iran | en |
| Type | Review Article | en |
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