Comparison Between Lidocaine Inhalation and Intravenous Dexamethasone in Reducing Postoperative Sore Throat Frequency After Laryngeal Mask Insertion
| Author | Susilo Chandra | en |
| Author | Pryambodho Pryambodho | en |
| Author | Annemarie Chrysantia Melati | en |
| Author | Rizki Iwan Kusuma | en |
| Orcid | Susilo Chandra [0000-0002-1440-4060] | en |
| Orcid | Pryambodho Pryambodho [0000-0002-8959-6394] | en |
| Orcid | Annemarie Chrysantia Melati [0000-0003-4945-6861] | en |
| Issued Date | 2018-10-31 | en |
| Abstract | Background: The frequency of postoperative sore throat (POST) after laryngeal mask airway insertion (LMA) was relatively high. Lidocaine might reduce the pain and inflammatory response. Additionally, inhalation form might result in a better distribution, which results in a better airway analgesia and minimal systemic effect. Objectives: To compare the incidence of sore throat post LMA insertion after 1.5 mg/kg of lidocaine inhalation and 10 mg of intravenous dexamethasone. Methods: This was a single-blinded randomized clinical trial, which included 128 patients who underwent ophthalmic surgery under general anesthesia with LMA insertion. Inclusion criteria were individuals 18 - 65 years old, ASA 1 or 2, Mallampati class I or II, and no sore throat before surgery. After University of Indonesia Research Ethical Committee approval and informed consent, all subjects were randomly divided into two groups: lidocaine inhalation group, which would receive lidocaine inhalation 2% 1.5 mg/kg (additional NaCl 0.9% until total 6 mL volume) and intravenous 2 mL NaCl 0.9%, and dexamethasone group, which would received NaCl 0.9% inhalation (6 mL volume) and dexamethasone 10 mg intravenously 10 minutes before LMA insertion. POST incidence and pain severity assessment were done 2 hours postoperatively. Statistical analysis were done with SPSS version 21. Results: There were 10.9% of subjects in the lidocaine inhalation group and 9.4% subjects in the dexamethasone group who suffer from POST postoperatively (P > 0.05). The median of POST pain in the lidocaine inhalation group was 0 (0 - 1), whereas in dexamethasone group it was 0 (0 - 3). This study did not find any side effects on both groups. Conclusions: Lidocaine inhalation 1.5 mg/kg was proportional to intravenous dexamethasone 10 mg in reducing the incidence and severity of POST after LMA insertion. | en |
| DOI | https://doi.org/10.5812/aapm.82131 | en |
| Keyword | Laryngeal Mask Airway | en |
| Keyword | Sore Throat | en |
| Keyword | Lidocaine | en |
| Keyword | Dexamethasone | en |
| Publisher | Brieflands | en |
| Title | Comparison Between Lidocaine Inhalation and Intravenous Dexamethasone in Reducing Postoperative Sore Throat Frequency After Laryngeal Mask Insertion | en |
| Type | Research Article | en |
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