The Effect of Okra (<i>Abelmoschus Esculentus</i>) On Fasting Blood Sugar, 2h PP Blood Sugar, Lipid Profile Level and, HbA1c in Patients with Type 2 Diabetes Mellitus (T2DM): Doubled-Blinded Randomized Trial
| Author | Afsaneh Raiesifar | en |
| Author | Asad Imani | en |
| Author | Yousef Veisani | en |
| Author | Alireza Vasiee | en |
| Orcid | Afsaneh Raiesifar [0000-0003-3286-2628] | en |
| Orcid | Asad Imani [0000-0002-6748-2986] | en |
| Orcid | Yousef Veisani [0000-0002-9131-3744] | en |
| Orcid | Alireza Vasiee [0000-0001-9401-7003] | en |
| Issued Date | 2025-09-30 | en |
| Abstract | Background: Type 2 diabetes mellitus (T2DM) is one of the most common metabolic diseases that burden patients both economically and physically. Supplementary therapies, such as herbal treatments, have been shown to control diabetes and reduce its symptoms. Objectives: This study aimed to discover the response of okra fruit on the metabolic and lipid profile indices in T2DM patients. Methods: In Ilam, Iran, in 2023, a double-blind randomized controlled trial was conducted on 60 participants with T2DM who were randomly allocated by dice tossing. The participants in the intervention group consumed four fresh okra fruits daily in water for four weeks, while the control group received only the routine nutrition program. At the beginning and end of the research, a 5-milliliter blood sample was obtained from all participants for laboratory analysis. Statistical tests included the chi-square, paired t-test, independent t-test, and difference-in-difference regression (DID), with a level of significance set at less than 0.05 in SPSS V.16. Results: Before the intervention, there were no significant differences in the mean scores of fasting blood sugar (FBS), 2 hours postprandial (2h PP), lipid profile, and HbA1c between the control and intervention groups (P > 0.05). After the intervention, significant differences were observed in the intervention group, with mean changes of -18.23 for FBS (95% CI: 175.11 to 187.15, P = 0.024), -41.84 for 2h PP (95% CI: 220.96 to 251.30, P = 0.009), -28.25 for triglyceride (TGC) (95% CI: 101.76 to 112.98, P = 0.047), -19.67 for total cholesterol (T. Chol) (95% CI: 130.24 to 150.56, P = 0.002), 7.47 for high density lipoprotein (HDL) (95% CI: 76.15 to 84.35, P = 0.020), -9.72 for low density lipoprotein (LDL) (95% CI: 47.22 to 58.72, P = 0.006), and -0.23 for HbA1c (95% CI: 7.02 to 7.22, P < 0.001), indicating a significant impact of the intervention on metabolic and lipid profile indices (P < 0.05). Additionally, assessing the group effect, time effect, and adjusting model showed that the intervention improved the metabolic and lipid profile indices in the intervention group (P < 0.05). Conclusions: Consuming okra fruit as an herbal supplement improves the metabolic and lipid profile indices in T2DM patients. | en |
| DOI | https://doi.org/10.5812/semj-159988 | en |
| Keyword | Okra | en |
| Keyword | Blood Sugar | en |
| Keyword | Lipid | en |
| Keyword | Diabetes | en |
| Keyword | Randomized Controlled Trial | en |
| Publisher | Brieflands | en |
| Title | The Effect of Okra (<i>Abelmoschus Esculentus</i>) On Fasting Blood Sugar, 2h PP Blood Sugar, Lipid Profile Level and, HbA1c in Patients with Type 2 Diabetes Mellitus (T2DM): Doubled-Blinded Randomized Trial | en |
| Type | Research Article | en |
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