A Complicated Case of Stroke, Epilepsy, and Mood Disorder: Hyperhomocysteinemia or Medication Cascade
| Author | Fatemeh Mohammadian | en |
| Author | Homayoun Amini | en |
| Author | Niayesh Mohebbi | en |
| Author | Amirhossein Jafari-Mehdiabad | en |
| Orcid | Niayesh Mohebbi [0000-0002-1420-7286] | en |
| Orcid | Amirhossein Jafari-Mehdiabad [0000-0003-2945-2919] | en |
| Issued Date | 2021-09-30 | en |
| Abstract | Introduction: Hyperhomocysteinemia is a risk factor for atherosclerosis and vascular disease, which is correlated with cerebral problems and various neurological disorders. Case presentation: We report a 20-year-old lady with a history of hyperhomocysteinemia affected with stroke, seizure, and mood disorder. By initiating medication for these illnesses, different complications appeared. During the hospital stay, drugs for treating a disease deteriorated the other. We encountered a complex patient and numerous ambiguities in her management. Conclusions: For patients with elevated serum homocysteine and psychiatry disorders, it is important to consider MTHFR gene mutation. A challenge in these patients is to select the medication that does not deteriorate hyperhomocysteinemia. In this complex case, we used carbamazepine that was accompanied by clinical improvement. | en |
| DOI | https://doi.org/10.5812/ijpbs.107679 | en |
| Keyword | Epilepsy | en |
| Keyword | Homocysteine | en |
| Keyword | Hyperhomocysteinemia | en |
| Keyword | Mood Disorder | en |
| Keyword | MTHFR Deficiency | en |
| Keyword | Stroke | en |
| Publisher | Brieflands | en |
| Title | A Complicated Case of Stroke, Epilepsy, and Mood Disorder: Hyperhomocysteinemia or Medication Cascade | en |
| Type | Case Report | en |