The Effect of Moderate Hypothermia on Renin- Angiotensin- Aldosterone System in Male Rats
| Author | M Kourosh Arami | en |
| Author | S Khamenei | en |
| Author | N Zarghami | en |
| Author | M Vahabian | en |
| Issued Date | 2005-07-31 | en |
| Abstract | Despite the diversity of studies on hypothermia, many of its biologic and physiologic effects are still poorly recognized. In this study the effect of hypothermia on the renin- angiotensin- aldosterone axis was explored. Materials and Methods: Ten male albino wistar rats after anesthetizing by chloral hydrate (0.5 m1/100gr body weights) were cooled to 25oC. Before and just after hypothermia, and once every 24 hours for three days; serum levels of agiotensin I and aldosterone were measured, using the radioimmunoassay method. Plasma renin activity was also determineded by the standard formula for angiotensin determinates at two temperatures of 4oC and 37oC. Results: Plasma renin activity increased during hypothermia but then decreased to a level not significantly different from basal values. Angiotensin I increased significantly in the second sample taken 24 hours following hypothermia (p | en |
| DOI | https://doi.org/ | en |
| Keyword | Hypothermia | en |
| Keyword | Renin- angiotensinaldosterone | en |
| Keyword | Rat | en |
| Publisher | Brieflands | en |
| Title | The Effect of Moderate Hypothermia on Renin- Angiotensin- Aldosterone System in Male Rats | en |
| Type | Research Article | en |
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