Effects of extremely low-frequency electromagnetic fields on learning and memory and anxiety-like behaviors in rats

Abstract

Introduction: Although past research has suggested that acute exposure to the extremely low-frequency electromagnetic fields (ELFEFs) can impair cognitive functions, data on chronic exposure remained scare. Only a few studies investigated the effects of chronic ELFEFs on cognitive functions, but the results are controversial. Thus, the aim of the present study was to study whether chronic exposure to ELFEFs can affect cognitive functions and anxiety-like behaviors in rats. Materials and Methods: Thirty-five male Wistar were divided into control and exposed (10 or 100 uT). Exposed rats were continuously exposed to a 50 Hz magnetic field of 10 or 100 µT for four weeks. Then, cognitive functions of all rats were tested in the Morris water maze and passive avoidance tasks. Also, anxiety-related behaviors of all rats were examined in the elevated- plus maze and light-dark box. Results: No significant differences were found between control and exposed in learning acquisition, memory retention and anxiety-related behaviors. Conclusion: Our results showed that chronic exposure to ELFEFs neither change cognitive functions nor anxiety-related behaviors in rats.