Impact of Gender and Age-at-onset on Clinical and Medical Features of Rheumatoid Arthritis in Western Algerian Population
| Author | Siheme Ouali | en |
| Author | Khalida Zemri | en |
| Author | Khedoudja Kanoun | en |
| Author | Harir Noria | en |
| Author | Feriel Sellam | en |
| Author | Zahira Benaissa | en |
| Author | Sid Tadj Hebri | en |
| Author | Ouassini Bensaber | en |
| Author | Douniazad Elmehadji | en |
| Author | Zouaoui Nadji | en |
| Orcid | Siheme Ouali [0000-0002-1767-3397] | en |
| Orcid | Khalida Zemri [0000-0002-5239-5046] | en |
| Orcid | Harir Noria [0000-0002-5221-2705] | en |
| Orcid | Feriel Sellam [0000-0003-4423-5699] | en |
| Issued Date | 2022-01-31 | en |
| Abstract | Background: This study aimed to demonstrate the gender and age-at-onset differences in rheumatoid arthritis (RA) in the western Algerian population and their impacts on patients' clinical features and medical management. Methods: A retrospective cross-sectional study was carried out at the Internal Medicine and Functional Rehabilitation Departments (University Hospital of Sidi-bel-Abbes region) based on medical records of over 306 RA patients diagnosed between 2016 and 2019 according to ACR 1987 criteria. Late-onset RA (LORA) was defined as disease onset at 51 years of age or older. All data were processed and analyzed via SPSS 22.0. Results: We enrolled 306 rheumatoid arthritis patients (85% women) with a mean age-at-onset of 52.47 ± 12.14. Algerian RA women were more at risk of developing type 2 diabetes (P = 0.035), hypertension (P = 0.003), and thyroid disorders (P = 0.05). We did not find any significant relationship between clinical features, laboratory data, and gender. The LORA group comprised 60.5% of our study population with a higher number of comorbidities such as hypertension (P < 0.001), osteoporosis (P = 0.007), and scleroderma (P = 0.014). Nonetheless, we found evidence of an association between positive anti-CCP, RF rate, and age-at-onset (P = 0.001 and P < 0.001, respectively). Conclusions: Algerian RA women with LORA presented a higher prevalence of comorbidities, while Young-onset RA (YORA) was associated with a high rate of RF. | en |
| DOI | https://doi.org/10.5812/zjrms.108918 | en |
| URI | https://brieflands.com/journals/zjrms/articles/108918 | en |
| Keyword | Young-onset RA (YORA) | en |
| Keyword | Late-onset RA (LORA) | en |
| Keyword | Algerian Patients | en |
| Keyword | Rheumatoid Arthritis (RA) | en |
| Keyword | Comorbidities | en |
| Keyword | Gender | en |
| Publisher | Brieflands | en |
| Title | Impact of Gender and Age-at-onset on Clinical and Medical Features of Rheumatoid Arthritis in Western Algerian Population | en |
| Type | Research Article | en |
Files
Original bundle
1 - 1 of 1
Loading...
- Name:
- zjrms-24-1-108918.pdf
- Size:
- 196.46 KB
- Format:
- Adobe Portable Document Format
- Description:
- Article/s PDF