The XmnI Polymorphic Site at 5' to Gγ Gene and its Correlation to the HBF Level and Gγ: Aγ Ratio in β-Thalassemia the Major and the Intermediate Patients from Kermanshah
| Author | Hooshang Nemati | en |
| Author | Z Rahimi | en |
| Author | Gh Bahrami | en |
| Author | H Nomani | en |
| Author | M Rezaei | en |
| Issued Date | 2008-03-20 | en |
| Abstract | Introduction: Beta Thalassemia is the most common inherited bloody disorder, affecting synthesis of the beta globin chain of hemoglobin. The type of β-Thalassemia mutation affects on the β-globin chain synthesis that appears as β° ،β +andβ++-Thalassemia. The presence of XmnI polymorphic site at the 5َ region of the Gγ-globin gene affects on the rate of Gγ chain synthesis and in some conditions influences on the production of HbF. These effects are important in the view of presentation of clinical symptoms in β-Thalassemia patients. | en |
| DOI | https://doi.org/ | en |
| Keyword | Thalassemia | en |
| Keyword | HbF | en |
| Keyword | Gγ chain percent | en |
| Keyword | XmnI polymorphism | en |
| Publisher | Brieflands | en |
| Title | The XmnI Polymorphic Site at 5' to Gγ Gene and its Correlation to the HBF Level and Gγ: Aγ Ratio in β-Thalassemia the Major and the Intermediate Patients from Kermanshah | en |
| Type | Research Article | en |
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