The Role of Systems Biology and Synthetic Biology in Appearing and Managing COVID-19

Abstract

Introduction: Studies reveal that viruses play important roles in the origins of cellular life and the evolution of all mammals for example. COVID-19 as a modified brutal virus has affected daily life and is slowing down the global economy.? The main purpose of the current study stems from the question that how COVID-19 was created and how it will be solved. Method: In order to conduct the present research, 26 English articles were chosen from among 57 articles published from 2000 to 2020 based on their relation to viral diseases and the availability of the full text at the PubMed, Science Direct, ProQuest, and Google Scholar databases. Findings: To study the new coronavirus, its genetic sequence should be accessible for us. As understood, synthetic biology takes advantage of the knowledge obtained from systems biology analysis and the conceptual tools made for such purposes. These approaches develop systems toxicology as well as stand out in predicting and evaluating the immunogenicity of vaccines as well as improving vaccine formulations through a definite immunological marker. Conclusion and Suggestion:Dealing with viral diseases such as COVID-19 demands vast knowledge of biotechnology, cell and molecular biology expertise, and competent approaches based on bioinformatics technology that contains systems biology and synthetic biology. Therefore, such scientific fields need to be highly developed in developing countries to keep their immunity and national security under warranty encountering any biological invasion, most specifically of viral types.