Exploring the Relationship Between Obsessive-Compulsive Disorder and Chronic Prostatitis/Chronic Pelvic Pain Syndrome: A Case-Control Study

AuthorAyoub Salehi Mishanien
AuthorSeyed Shahab Banihashemen
AuthorAmir Alinejad Khorramen
AuthorShadi Kordbachehen
AuthorFarzad Allamehen
OrcidAyoub Salehi Mishani [0009-0003-1981-6405]en
OrcidSeyed Shahab Banihashem [0000-0002-4192-0079]en
OrcidAmir Alinejad Khorram [0000-0002-5931-1036]en
OrcidShadi Kordbacheh [0000-0001-6249-0250]en
OrcidFarzad Allameh [0000-0003-4536-6404]en
Issued Date2025-03-31en
AbstractBackground: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is recognized as a challenging condition with unclear underlying factors. Despite the difficulties in treatment, psychological factors are thought to contribute to its symptoms. Objectives: This investigation sought to examine the correlation between obsessive-compulsive disorder (OCD) and CP/CPPS. Methods: We assembled a case group comprising 30 patients diagnosed with CP/CPPS and a control group consisting of 30 healthy individuals without the condition. The Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) was used to assess the prevalence of OCD in both groups. In contrast, the National Institutes of Health (NIH) Chronic Prostatitis Symptom Index (NIH-CPSI) was used to evaluate the severity of CP/CPPS symptoms. Results: The findings revealed no statistically significant difference in the prevalence of OCD between the group of individuals with CP/CPPS and the healthy control group. However, patients with CP/CPPS had significantly higher Y-BOCS scores compared to the control group. Furthermore, we observed a significant positive correlation between Y-BOCS scores and NIH-CPSI scores, suggesting that increasing OCD symptoms were associated with increased disease severity, pain, and decreased quality of life. Multivariate analysis revealed that increasing Y-BOCS scores independently predicted CP/CPPS symptom severity. Conclusions: Our findings highlight the importance of considering psychological factors, including OCD, in the management of CP/CPPS. The results suggest that addressing OCD symptoms may be an important adjunctive treatment approach for improving symptom outcomes in patients with CP/CPPS. Future studies should investigate the effectiveness of psychotherapeutic interventions targeting OCD in this population.en
DOIhttps://doi.org/10.5812/ijpbs-151592en
KeywordObsessive-Compulsive Disorderen
KeywordProstatitisen
KeywordPsychosomatic Disordersen
PublisherBrieflandsen
TitleExploring the Relationship Between Obsessive-Compulsive Disorder and Chronic Prostatitis/Chronic Pelvic Pain Syndrome: A Case-Control Studyen
TypeResearch Articleen

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