Prevalence and Risk Factors for Non-Vertebral Fractures in Patients Receiving Oral Glucocorticoids
| Author | Sosa-HenrIquez Manuel | en |
| Author | Gomez de Tejada-Romero Maria Jesus | en |
| Author | Saavedra-Santana Pedro | en |
| Author | Blazquez-Cabrera Jose Antonio | en |
| Author | Garcia-Vadillo Jess Alberto | en |
| Author | Valdes-Llorca Carmen | en |
| Author | Diaz-Curiel Manuel | en |
| Author | Munoz-Torres Manuel | en |
| Author | Martinez-Rodriguez Maria Elena | en |
| Author | Navarro-Ceballos Carmen | en |
| Author | Sanfelix-Genoves Jose | en |
| Author | Cancelo-Hidalgo Maria Jesus | en |
| Author | Carpintero-Benitez Pedro | en |
| Author | Mesa-Ramos Manuel | en |
| Author | Palacios-Gil Antunano | en |
| Issued Date | 2012-12-01 | en |
| Abstract | Background: Glucocorticoids taken orally increase the risk of fractures. It has been noted that a dose as low as 2.5 mg/day increases the risk of vertebral fracture. What is less clear is the possible influence of other risk factors for osteoporosis on the presence of non-vertebral fractures in patients taking glucocorticoids. Objectives: A cross-sectional study, performed on 513 men and women from Spain, who were taking at least 7.5 mg/day of oral prednisone for a minimum of 3 months. A questionnaire was developed, through which information on risk factors was collected. Patients and Methods: A cross-sectional study, performed on 513 men and women from Spain, who were taking at least 7.5 mg/day of oral prednisone for a minimum of 3 months. A questionnaire was developed, through which information on risk factors was collected. Results: 28.3% of the patients who were taking glucocorticoids at a daily oral dose of 7.5 mg/day for a minimum of 3 months had suffered at least one non-vertebral fracture. The risk increased with age, the number of months the glucocorticoids had been taken, the presence of falls in the last year and, above all, with a maternal history of hip fracture. Conclusions: In patients taking oral glucocorticoids for over 3 months at doses higher than 7.5 mg/day of prednisone or equivalent, the prevalence of non-vertebral fractures was 28.3%. Some risk factors associated with the presence of these fractures were identified. The duration of glucocorticoid use appears to be more strongly related to the presence of non-vertebral fractures than the daily dose. | en |
| DOI | https://doi.org/10.5812/ijem.3442 | en |
| URI | https://brieflands.com/journals/ijem/articles/74984 | en |
| Publisher | Brieflands | en |
| Title | Prevalence and Risk Factors for Non-Vertebral Fractures in Patients Receiving Oral Glucocorticoids | en |
| Type | Research Article | en |
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