Hindlimb Unloading Effects on β-Endorphin Receptor in Rats
| Author | Iraj Mirzaii Dizgah | en |
| Author | Pedram Bagheri Chimeh | en |
| Author | Bahareh Tavakoli Far | en |
| Orcid | Iraj Mirzaii Dizgah [0000-0002-0050-4191] | en |
| Issued Date | 2018-07-31 | en |
| Abstract | Background: Space is a harsh environment that affects the body in many ways. Humans venturing into the environment of space can have negative effects on the body. Objectives: This study focused on the effects of simulated microgravity on β-endorphin receptor concentration. Methods: Rats (n = 16) were divided in two groups (n = 8/group), freely moving (control group) and hindlimb unloading. A rat-tail suspension model was used in experiment groups for 14 days to explore the effect of simulated microgravity on the β-endorphin receptor concentration in the hippocampus, brain stem, and prefrontal cortex. Results: The results showed that the concentration of β-endorphin receptor in the brain stem and prefrontal cortex, but not in hippocampus, was significantly higher in hindlimb unloading rats than controls. Conclusions: It is possible that simulated microgravity may increase the β-endorphin receptor expression in the prefrontal cortex and brain stem in the rat. | en |
| DOI | https://doi.org/10.5812/archneurosci.62975 | en |
| Keyword | Hindlimb Unloading | en |
| Keyword | Hippocampus | en |
| Keyword | Prefrontal Cortex | en |
| Keyword | Beta-Endorphin | en |
| Keyword | Receptor | en |
| Publisher | Brieflands | en |
| Title | Hindlimb Unloading Effects on β-Endorphin Receptor in Rats | en |
| Type | Research Article | en |
Files
Original bundle
1 - 1 of 1
Loading...
- Name:
- ans-5-3-62975.pdf
- Size:
- 211.07 KB
- Format:
- Adobe Portable Document Format
- Description:
- Article/s PDF