The Effect of ACEI/ARB on the Outcomes of COVID-19 Hospitalized Patients
| Author | Tahereh Sabaghian | en |
| Author | Minoo Heidari Almasi | en |
| Author | Farzaneh Futuhi | en |
| Author | Minoosh Shabani | en |
| Author | Azam Erfanifar | en |
| Author | Seyed Alireza Ebadi | en |
| Orcid | Tahereh Sabaghian [0000-0001-7689-8150] | en |
| Orcid | Minoo Heidari Almasi [0000-0001-8058-6467] | en |
| Orcid | Minoosh Shabani [0000-0002-4064-8325] | en |
| Issued Date | 2022-05-31 | en |
| Abstract | Considering that there are different reports about the effects of angiotensin II type-I receptor blockers (ARB) and angiotensin-converting enzyme inhibitors (ACEI) on the outcomes of the patients with COVID-19, we aimed to conduct this retrospective study on 138 hypertensive patients (81 ACEI/ARB users) to assess the patients’ outcomes by comparing ACEI/ARB and non-ACEI/ARB users. Multivariate adjusted cox regression model, by considering the effect of other variables, demonstrated that increased age (HR = 1.04, 95% CI = 1.01 -1.07, P =0.003) and non- ACEI/ARB users (HR = 2.12 95% CI = 1.12 - 4.13, P = 0.021) were associated with increased risk of in-hospital mortality in about one week follow-up. In conclusion, we found that in-hospital mortality was lower in ACEI/ARB users, showing the positive effect of these treatments on patients’ outcomes. | en |
| DOI | https://doi.org/10.5812/numonthly-121819 | en |
| Keyword | COVID-19 | en |
| Keyword | Hypertension | en |
| Keyword | Mortality | en |
| Keyword | Angiotensin-converting Enzyme Inhibitor | en |
| Keyword | Angiotensin Receptor Blockers | en |
| Publisher | Brieflands | en |
| Title | The Effect of ACEI/ARB on the Outcomes of COVID-19 Hospitalized Patients | en |
| Type | Brief Report | en |
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