Comparison of intramuscular syntometrine and intravenous oxytocin in management of the third stage of labor
| Author | F Movahed | en |
| Author | H Abbasi | en |
| Issued Date | 2007-09-30 | en |
| Abstract | Abstract Background: One of the main etiologies of maternal mortality is obstetrical hemorrhage. The first step in decreasing hemorrhage is the use of uterotonic drugs in the third stage of labor. Objective: To compare the efficacy and safety of intravenous oxytocin and intramuscular syntometrine in management of the third stage of labor. Methods: This randomized double blind clinical trial was carried out at Kosar Hospital, Qazvin (Iran) in 2005. A total of 800 women having a singleton pregnancy and vaginal delivery were randomized to receive either 1 ml of syntometrine intramuscularly, or 10 units of intravenous oxytocine following delivery of the anterior shoulder of fetus. Hemoglobin level pre- and 24 hours post-delivery, duration of third stage, need for re-administration of uterotonic drugs, need for manual removal of placenta, and unpleasant side effects including nausea, vomiting, headache and hypertension were recorded. The data were analyzed using chi-square test. Findings: Mean drop percent of hemoglobin level in oxytocin group was 3.7±2.54% and in syntometrine group 3.6±2.49% with no significant difference, statistically. There was also no statistically significant difference between the need for re-administration of uterotonic drugs, duration of third stage of labor, need for manual removal of placenta and the maternal side effect in two groups. Conclusion: Regarding the efficacy and side effects of intravenous oxytocin and intramuscular syntometrine, no difference was found. | en |
| DOI | https://doi.org/ | en |
| Keyword | Keywords: Oxytocin | en |
| Keyword | Syntometrine | en |
| Keyword | Labor | en |
| Keyword | Hemorrhage | en |
| Publisher | Brieflands | en |
| Title | Comparison of intramuscular syntometrine and intravenous oxytocin in management of the third stage of labor | en |
| Type | Research Article | en |
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